Postnatal germ cell development in cryptorchid boys
نویسندگان
چکیده
منابع مشابه
Testicular gene expression in cryptorchid boys at risk of azoospermia.
Despite timely and successful surgery, 32% of patients with bilateral and 10% with unilateral cryptorchidism will develop azoospermia. Cryptorchid boys at risk of azoospermia display a typical testicular histology of impaired mini-puberty at the time of the orchidopexy. During mini-puberty increased gonadotropin and testosterone secretion stimulate transformation of gonocytes into Ad spermatogo...
متن کاملTesticular neoplasia in cryptorchid boys at primary surgery: case series.
Chobot (Poland); G Joner (Norway); D Michalkova (Slovakia); C Patterson (Northern Ireland); P Pozzilli (Italy, Lazio); AG Schranz (Malta); P Smail (Scotland); M Songini (Italy, Sardinia); B Urbonaite (Lithuania); E Wadsworth (British Paediatric Survey, UK). Funding: The European diabetes (EURODIAB) research network is supported by the European Commission medical research programme (contracts BM...
متن کاملGerm cell development in the postnatal testis: the key to prevent malignancy in cryptorchidism?
To permit normal postnatal germ cell development, the mammalian testis undergoes a complex, multi-staged process of descent to the scrotum. Failure of any part of this process leads to congenital cryptorchidism, wherein the malpositioned testis finds itself at the wrong temperature after birth, which leads to secondary germ cell loss and later infertility and risk of cancer. Recent studies sugg...
متن کاملprevalence of intratubular germ cell neoplasia in cryptorchid testes of infertile men
background: cryptorchidism is a common malformation in neonates; surgery or medical treatments are applied during childhood. untreated cryptorchid testes are in the risk of intratubular germ cell neoplasia (igcn) and consequently invasive testicular tumors which could be shown by immunohistochemistry staining for placental like acid phosphatase (plap) marker. objective: we designed this study t...
متن کاملPrevalence of intratubular germ cell neoplasia in cryptorchid testes of infertile men
BACKGROUND Cryptorchidism is a common malformation in neonates; surgery or medical treatments are applied during childhood. Untreated cryptorchid testes are in the risk of intratubular germ cell neoplasia (IGCN) and consequently invasive testicular tumors which could be shown by immunohistochemistry staining for placental like acid phosphatase (PLAP) marker. OBJECTIVE We designed this study t...
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ژورنال
عنوان ژورنال: Asian Journal of Andrology
سال: 2020
ISSN: 1008-682X
DOI: 10.4103/aja.aja_48_19